What we do

STAMINA methodology

We leverage the diverse expertise an organization or community already has. We combine this input with peer-reviewed evidence and real-world population-level outcomes, to estimate how programs and policies impact fatalities, negative health outcomes, and costs avoided, budget by budget.

STAMINA is SUDenomics’ methodology for developing applied health-economic models in addiction, applying actuarial concepts to the problem. A model built with it estimates the impact of an intervention through time. It is designed to be simple and understandable, with assumptions that are clear to communicate.

Visualizing a STAMINA-built model

The model tracks a population across the experiences a person with a substance use disorder may go through. It represents the disease as a finite set of possible circumstances an individual could be in at any given time. Each month, it projects how many people remain where they are and how many move to a new presentation of the disease, represented uniquely in the model. Each unique presentation has corresponding health outcomes and costs, which can be considered from a variety of perspectives depending on project scope.

The model repeats this calculation monthly over many years. Separate projections are run for the status quo and for each intervention, so that evidence of an intervention’s success can be translated into long-term outcomes.

Of 100 people with the same disease presentation this month,where are they next month?100 peopleCurrently usingthis month87 continue using9 to treatment3 to early recovery1 fatalityIllustrative Of 100 people with the same diseasepresentation this month, where are they next month?100 peopleCurrently usingthis month87 continue using9 to treatment3 to early recovery1 fatalityIllustrative

Illustrative example: not calculated results

What a model produces: 1,000 people over their lifetime, with the intervention compared with the status quo

410

Years of life gained

560

Years of healthy life gained

2,100

Years in recovery gained

$21.6M

Cost avoided over a lifetime, in today’s dollars

Annual cost to all budgets, $M

Status quoWith the intervention
0246810YearStatus quoWith theinterventionCost avoided 0246810Cost avoidedYear

Cost avoided by budget, lifetime, $M

Healthcare9.8Criminal justice6.5Social services2.8Productivity2.5

Data related to long-term addiction outcomes is rare

Whether a hospital admission, a social benefit or an incarceration was driven by addiction is often unclear. Which indirect societal costs to include is often subject to debate. And because the course of the disease runs over years, it is harder to track, so there is less concrete data to project from.

The model addresses this by framing assumptions as three questions, answered by the people who know the population.

Published evidence is used to guide ranges where it exists. These figures are combined with the expertise and experience of the clinicians, people in recovery, agencies and budget owners who know the population. The model is flexible to test across ranges of values where opinions differ.

Disease presentations

What set of circumstances could someone with addiction be in?

In the projection, a person has exactly one disease presentation category at a time. These each carry a measure of health, a risk of death and a monthly cost that estimate averages of impacts across a cohort.

Transitions

Of 100 people with the same disease presentation this month, how are they expected to present next month?

Costs

What does each disease presentation cost, and which budgets and perspectives should be included?

Questions a decision-maker may ask

What an intervention is worth over the long term: health gained, deaths avoided and cost avoided, by year, in the budgets that carry them. The model is run once without the intervention and once with it; the difference is the result. A model of this kind supports a decision; it does not make one.

Ways to engage

Anyone interested in a conversation about the approach, or about a specific application, is invited to reach out.